In a longer term trial, adult outpatients n 326 who predominantly met dsm iv criteria for schizophrenia and who remained stable on olanzapine during open label treatment for at least 8 weeks were randomized to continuation on their current olanzapine doses ranging from 10 to 20 mg day or to placebo.
DATA COLLECTION AND ANALYSISData were independently extractedFor homogeneous dichotomous data the random effects relative riskRRthe 95confidence intervalsCIandwhere appropriatethe number needed to treatNNTwere calculated on an intention-to-treat basisFor continuous data the reviewers calculated weighted mean differences.
Increased potentialin adolescents as compared with adultsfor weight gain and hyperlipidemiaclinicians prescribing to adolescents should consider potential long-term riskswhich in many cases may lead them to prescription of other drugs first in this population.
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we spoke to his psychiatrist and she agreed that it would be in my brother s best interest to stay on zyprexa zydis and not switch to olanzapine generic version because he experienced problems with it in the past.