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Prograf may increase your chances of developing a serious infection.

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Grapefruit and grapefruit juice may interact with tacrolimus and lead to unwanted side effectsAvoid the use of grapefruit products while taking Prograf.

Take Prograf exactly as prescribed by your doctorFollow all directions on your prescription labelYour doctor may occasionally change your dose to make sure you get the best resultsDo not take this medicine in larger or smaller amounts or for longer than recommended.

Prograf is indicated for the prophylaxis of organ rejection in patients receiving allogeneic kidneytransplantsIt is recommended that Prograf be used concomitantly with azathioprine or mycophenolate mofetilMMFand adrenal corticosteroidssee Clinical StudiesTherapeutic drug monitoring is recommended for all patients receiving Prografsee DOSAGE AND ADMINISTRATION

Prograf can harm your kidneysand this effect is increased when you also use certain other medicines harmful to the kidneysBefore using Prograftell your doctor about all other medicines you useMany other drugsincluding some over-the-counter medicinescan be harmful to the kidneys.

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you may avoid consumption of grapefruit or its juice during a prograf medication.