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Caution should be exercised when coadministering mirtazapine with potent CYP3A4 inhibitorsHIV protease inhibitorsazole antifungalserythromycinor nefazodone.

Mirtazapine is a potent antagonist of 5-HT2 and 5-HT3 receptorsMirtazapine has no significant affinity for the 5-HT1A and 5-HT1B receptors.

This medication may be available under multiple brand names and/or in several different formsAny specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed hereAs wellsome forms of this medication may not be used for all of the conditions discussed here.

No suicides occurred in any of the pediatric trialsThere were suicides in the adult trialsbut the number was not sufficient to reach any conclusion about drug effect on suicide.

The following side effects have been reported by at least 1of people taking this medicationMany of these side effects can be managedand some may go away on their own over time.

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