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Misoprostol should be used with caution in patients with conditions that predispose them to diarrhoeasuch as inflammatory bowel diseaseTo minimise the risk of diarrhoeamisoprostol should be taken with foodand magnesium-containing antacids should be avoidedsee section 4.5
THE PATIENT SHOULD NOT GIVE Cytotec TO ANYONE ELSECytotec has been prescribed for the patient’s specific conditionmay not be the correct treatment for another personand may be dangerous to the other person if she were to become pregnant.
The risk of uterine rupture associated with misoprostol use in pregnancy increases with advancing gestational ages and prior uterine surgeryincluding Cesarean deliveryGrand multiparity also appears to be a risk factor for uterine rupture.
The Cytotec package the patient receives from the pharmacist will include a leaflet containing patient informationThe patient should read the leaflet before taking Cytotec and each time the prescription is renewed because the leaflet may have been revised.
Blood/Coagulationanemiaabnormal differentialthrombocytopeniapurpuraESR increased.
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