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For pediatric patients, viramune 150mg m day is the recommended dosage, which is to be taken once daily for 14 days and then twice daily.

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For patients less than 3 years and for all other age groupsan immediate-release oral suspension dosage form is availableplease refer to the respective Summary of Product Characteristics

Rhabdomyolysis has been observed in patients experiencing skin and/or liver reactions associated with nevirapine use.

A clinically not relevant increase in the apparent clearance of nevirapineby 9compared to historical data was reported.

Howeverpatients should be advised that they may experience adverse reactions such as fatigue during treatment with ViramuneThereforecaution should be recommended when driving a car or operating machineryIf patients experience fatigue they should avoid potentially hazardous tasks such as driving or operating machinery.

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children enrolled received weight or body surface area dose-adjusted immediate-release viramune in combination with other antiretrovirals for a minimum of 18 weeks and then were switched to viramune xr tablets in combination with other antiretrovirals for 10 days, after which steady-state pharmacokinetic parameters were determined.