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Zoloft administered daily throughout the menstrual cycle was statistically significantly more effective than placebo on change from baseline to endpoint on the drsp total score, the hamd-17 total score, and the cgi-s score, as well as the cgi-i score at endpoint.

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Sertraline oral tablet can interact with other medicationsvitaminsor herbs you may be takingAn interaction is when a substance changes the way a drug worksThis can be harmful or prevent the drug from working well.

False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking ZOLOFTThis finding is due to lack of specificity of the screening testsFalse-positive test results may be expected for several days following discontinuation of ZOLOFTConfirmatory testssuch as gas chromatography/mass spectrometrywill distinguish sertraline from benzodiazepines.

The effectiveness of ZOLOFT for the treatment of PMDD was established in two double-blindparallel groupplacebo-controlled flexible dose trialsStudies PMDD-1 and PMDD-2conducted over 3 menstrual cycles in adult female patientsThe effectiveness of ZOLOFT for PMDD for more than 3 menstrual cycles has not been systematically evaluated in controlled trials.

Efficacy was assessed with the Daily Record of Severity of ProblemsDRSPa patient-rated instrument that mirrors the diagnostic criteria for PMDD as identified in the DSM-IVand includes assessments for moodphysical symptomsand other symptomsOther efficacy assessments included the Hamilton Rating Scale for DepressionHAMD-17and the Clinical Global Impression Severity of IllnessCGI-Sand ImprovementCGI-Iscores.

Are there any major differences between Zoloft and other mental health medications?

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