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Femara is authorised in the EU via national proceduresThis has led to divergences across Member States in the way the medicine can be usedas seen in the differences in the summaries of product characteristicsSmPCslabelling and package leaflets in the countries where the medicine is marketed.

For use as extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy2.5 mg tablet orally administered once a day without regard to meals.

The optimal duration of treatment with Femara is not knownTreatment should be discontinued if there is a tumor relapse.

In postmenopausal womenAdjuvant treatment of hormone receptor positive early breast cancerExtended adjuvant treatment of early breast cancer after 5 years of adjuvant tamoxifen therapyFirst-line treatment of hormone receptor positive or unknownlocally advanced or metastatic breast cancerTreatment of advanced breast cancer with disease progression following antiestrogen therapy.

Femaraletrozolelowers estrogen levels in postmenopausal womenwhich may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

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